概述
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货号
DHE26399
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描述
Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
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种属反应性
Human -
克隆类型
Monoclonal -
靶标
CD79b -
浓度
1 mg/ml -
内毒素水平
Please contact with the lab for this information. -
纯度
>90% as determined by SEC. -
纯化方式
Purified by Ion Exchange Chromatography. -
克隆号
Polatuzumab vedotin-piiq
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应用
Research Grade Biosimilar -
状态
Liquid -
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. -
别名
Polivy
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