Anti-Tocilizumab Polyclonal Antibody (PAC36902)

Rabbit

IgG

Polyclonal

Tocilizumab

ELISA: 1:4000-1:8000

Rabbit polyclonal to Actemra.

The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays.

0.85 mg/ml

Purified by antigen affinity column.

CAS: 375823-41-9

ELISA

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects.