Anti-Eculizumab Polyclonal Antibody (PAB90001)

Rabbit

IgG

Polyclonal

Eculizumab

ELISA: 1:4000-1:8000

Rabbit polyclonal to Soliris.

The product is specific for Eculizumab. This antibody serves as an excellent positive control for Eculizumab immunogenicity (ADA) assays.

0.5 mg/ml

Purified by antigen affinity column.

CAS: 219685-50-4

ELISA

Liquid

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5, or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.