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货号
EHD00601
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描述
Tissue factor, also called platelet tissue factor, factor III, or CD142, is a protein encoded by the F3 gene, present in subendothelial tissue and leukocytes. CD142, also known as ,Coagulation Factor III, and Thromboplastin, is a 45 kD type I transmembrane glycoprotein. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis, atherosclerosis, and cancer. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells, fibroblasts, keratinocytes, glomerular epithelial cells (cytoplasmic inclusions), astrocytes, myocardium, liver stromal cells, pancreas cells, and is also expressed on activated monocytes and stimulated endothelial cells.
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表达系统
Mammalian Cells -
种属
Homo sapiens (Human) -
蛋白长度
Met1-Glu251 -
预测分子量
29.24 kDa -
性质
Recombinant -
内毒素水平
Please contact with the lab for this information. -
纯度
>90% as determined by SDS-PAGE. -
Accession号
P13726 -
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress -
状态
Lyophilized -
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. -
重悬
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. -
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. -
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. -
别名
Tissue factor, CD142, F3, Thromboplastin, Coagulation factor III, TF
